Ankylosing Spondylitis symptoms and its Treatment

Fuse Infusion offers Biological Therapy Treatment for Ankylosing Spondylitis.

There are various chronic autoimmune diseases; among them, Ankylosing Spondylitis is one. It is a type of condition that causes pain in the lower back of a patient. It is a highly-inflammatory form of arthritis, and due to this, a patient experiences chronic pain. Fuse Infusion offers Biological Therapy Treatment for Ankylosing Spondylitis

There are multiple causes that can result in Ankylosing Spondylitis, and if you have any of the conditions, such as ulcerative colitis, Crohn’s disease, and psoriasis. You can likely also have ankylosing spondylitis.

Ankylosing spondylitis may have various presentations such as stiffness in the back, hip pain, and many others. But, if you are diagnosed with this chronic autoimmune disease, don’t worry, as Fuse Infusion offers you biological therapy treatment.

Ankylosing Spondylitis

A type of arthritis known as ankylosing spondylitis results in chronic (long-term) inflammation of the spine. The sacroiliac joints, which are situated between the base of the spine and the pelvis, are affected by ankylosing spondylitis (AS).

 One of the first indications of AS is this inflammation, known medically as sacroiliitis. The joints between the bones, the vertebrae that make up the spinal column, are frequently affected by inflammation. Spondylitis is the name of this illness.

Some ankylosing spondylitis sufferers have chronic back and hip pain and stiffness. Others experience sporadic, weaker symptoms. The spine may become inflexible as a result of new bone formations that eventually fuse vertebral segments. This condition is known as ankylosis.

This chronic disease ankylosing spondylitis belongs to a disease group known as spondyloarthropathies. In the United States, one individual has ankylosing spondylitis between three to 13 out of a thousand Americans.

How Will Fuse Infusion Support You During Biologic Infusion Therapy?

At Fuse Infusion, we offer biological infusion therapy to patients diagnosed with chronic autoimmune diseases. We offer treatment in a safe and secure setting and ensure our full support during the infusion procedure.

We have highly qualified and expert medical professionals who constantly monitor you for allergies or side effects after receiving biological infusions.

Causes of Ankylosing Spondylitis

Human leukocyte antigen-B gene (HLA-B) variations are present in approximately 95% of individuals who are diagnosed with ankylosing spondylitis. This altered or mutated gene results in the production of the disease-risking HLA-B27 protein.

However, most HLA-B gene mutation carriers do not get ankylosing spondylitis. In actuality, 80% of children who receive the faulty gene from an AS parent do not go on to have the condition. The illness has been connected to more than 60 genes.

Moreover, in addition to this, if you are diagnosed with any of the below-mentioned conditions. Your chances of getting diagnosed with ankylosing spondylitis will increase:

  • Ulcerative colitis
  • Crohn’s disease
  • Psoriasis

Ankylosing Spondylitis Symptoms

The symptoms of ankylosing spondylitis will start appearing between the age of 17 to 45 years. However, these symptoms may develop in younger children and in older adults.

Sometimes, patients with ankylosing spondylitis may experience some mild symptoms, but sometimes the pain can be persistent in the body of a patient.

The ankylosing spondylitis symptoms may vary on and off, but they may worsen or improve with time. Ankylosing spondylitis can cause the following symptoms:

  • Hip pain
  • Lowe’s back stiffness and pain
  • Neck pain
  • Joint pain
  • Fatigue
  • Difficulty in breathing
  • Unexpected weight loss
  • Loss of appetite
  • Diarrhea
  • Abdominal pain
  • Vision problems
  • Skin rash

If any of these symptoms appear, you may have ankylosing spondylitis. Contact Fuse Infusion immediately for the treatment process to overcome this problem.

Ankylosing Spondylitis Treatment

Biologics are the new and advanced treatment for ankylosing spondylitis, an inflammatory form of arthritis mostly affecting the spine. They are genetically produced by living organisms.

They are an immune system-focused subset of disease-modifying anti-rheumatic medications (DMARDs). Inflammatory immune system proteins, including tumor necrosis factor (TNF) and interleukin 17 (IL17), are specifically targeted by biologics.

Most biological treatments for ankylosing spondylitis function by preventing or suppressing TNF, a protein crucial in starting the inflammation that can result in painful and swollen joints.

Following are the five TNF inhibitors that have been approved for treating ankylosing spondylitis:

  • Adalimumab
  • Etanercept
  • Certolizumab
  • Golimumab
  • Infliximab

Moreover, in addition to this, two more genetically engineered biologics are specially designed for blocking IL-17. This is a different inflammation trigger. These biologics are also approved:

  • Secukinumab
  • Ixekizumab

These medications function by attaching to IL-17, a protein that initiates inflammation as a normal immunological response in your body. IL-17 levels in ankylosing spondylitis sufferers may be higher than usual, resulting in excessive inflammation.

As a first step of ankylosing spondylitis treatment, we recommend anti-inflammatory drugs (NSAIDs). If, in case, they won’t function well in treating the condition, our professionals then move towards the other biologics.

Biologics help reduce the stiffness and back pain associated with ankylosing spondylitis. They are thought to increase physical function, lessen fatigue, and lessen inflammatory back pain, enhancing the quality of life for those with ankylosing spondylitis.

A traditional DMARD, like sulfasalazine or methotrexate, could be recommended if ankylosing spondylitis also affects the joints in your arms and legs.

If you see some emergency symptoms after receiving the biologics, you should consult us immediately.

Contact Fuse Infusion for Ankylosing Spondylitis Treatment

If your doctor has recommended biological therapy treatment for ankylosing spondylitis, we at Fuse Infusion offer you the best treatment services. We treat ankylosing spondylitis through medications, which are specialized biologics, and help our patients in overcoming this chronic disease.

Each Fuse Infusion patient receives direct care and treatment from our licensed professionals throughout biological infusion therapy, providing thorough medical management. 

From start to end, each patient receives individualized care. When required, on-call medical professionals are accessible.

At Fuse Infusion, we believe in offering premium-quality services to our patients. So, contact us to receive a biological infusion today!