Severe Asthma

Severe Asthma Symptoms, Causes and Treatment

Asthma is an inflammatory lung disease with symptoms ranging from mild to severe. Most asthma can be controlled by avoiding triggers, taking daily medications, and using additional treatment methods.

However, if your asthma cannot be controlled with any treatment, it is considered severe. In addition to other daily treatments, severe asthma may necessitate substantial dosages of inhaled corticosteroids or long-term oral corticosteroids.

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Severe Asthma

Severe asthma is a chronic respiratory condition characterized by persistent and uncontrolled symptoms despite appropriate treatment. Unlike mild or moderate asthma, asthma poses unique challenges and requires specialized management. Here are key aspects of understanding about severe asthma:

Symptoms: Severe asthma symptoms are similar to those of mild or moderate asthma but tend to be more frequent, intense, and resistant to conventional treatments. Common symptoms include wheezing, shortness of breath, chest tightness, and coughing, which can significantly impact daily activities and quality of life.


Diagnosis: Severe asthma is diagnosed when an individual’s symptoms and lung function show persistent limitations despite using high-dose inhaled corticosteroids and additional asthma medications. It’s crucial to undergo a thorough evaluation by a healthcare professional specializing in respiratory disorders to confirm the diagnosis and rule out other conditions.

Triggers: Like all types of asthma, severe asthma can be triggered by various factors such as allergens (pollen, dust mites), irritants (tobacco smoke, pollution), respiratory infections, exercise, and emotional stress. Identifying and minimizing exposure to triggers is an essential part of managing asthma.

Assessing Asthma Severity

Asthma severity is evaluated based on the frequency and intensity of symptoms, lung function measurements, and the level of medication required to control symptoms. Healthcare providers may use standardized tools, such as asthma severity charts, to assess the severity of asthma. These charts classify asthma severity into several categories, ranging from intermittent to mild, moderate, and severe persistent asthma.

Understanding your asthma severity helps guide treatment decisions and determine the appropriate medications and management strategies.

Treatment Approaches for Severe Asthma

Biologic infusion therapy has emerged as a breakthrough treatment option for individuals with severe asthma who have not responded well to conventional therapies. This specialized therapy involves the administration of biologic medications through intravenous infusions, targeting specific immune pathways involved in asthma inflammation.

Here’s how biologic infusion therapy can help in treating asthma:

Targeted Inflammation Reduction: 

Biologic medications used in infusion therapy are designed to target specific molecules or cells that play a key role in the inflammatory process of asthma. For example, monoclonal antibodies can target and neutralize specific immune system proteins, such as immunoglobulin E (IgE) or interleukins, which are known to contribute to asthma inflammation. 

By blocking these inflammatory pathways, biologic infusions help reduce airway inflammation, bronchial hyperresponsiveness, and asthma symptoms.

Reduction in Exacerbations: 

Severe asthma is often characterized by frequent and exacerbations or asthma attacks. These exacerbations can be life-threatening and significantly impact an individual’s quality of life. Biologic infusion therapy has shown effectiveness in reducing the frequency and severity of asthma exacerbations. By modulating the immune system and reducing airway inflammation, biologics help stabilize asthma symptoms and decrease the risk of acute exacerbations.

Improved Lung Function: 

Severe asthma is associated with persistent airflow limitation and reduced lung function. Biologic infusion therapy has demonstrated the potential to improve lung function in individuals with severe asthma. By targeting specific inflammatory pathways, these medications help restore airway function, reduce airway remodeling, and improve overall lung capacity and airflow.

Enhanced Symptom Control: 

Asthma symptoms can be debilitating, affecting daily activities and quality of life. Biologic infusions have shown efficacy in improving symptom control in individuals with severe asthma. By effectively reducing airway inflammation and hyperresponsiveness, these medications can alleviate symptoms such as wheezing, coughing, shortness of breath, and chest tightness.

Reduction in Medication Dependence:

Severe often requires high doses of oral corticosteroids and multiple medications to manage symptoms. Long-term use of oral corticosteroids can lead to significant side effects. Biologic infusion therapy offers an alternative treatment approach that can help reduce the reliance on oral corticosteroids and other asthma medications. By achieving better asthma control, individuals may be able to taper off oral corticosteroids or reduce the dosage, minimizing potential side effects associated with long-term steroid use.

It’s important to note that biologic infusion therapy for asthma is a specialized treatment option that is typically reserved for individuals who have not adequately responded to other asthma medications.

The specific biologic medication prescribed will depend on individual factors, such as the underlying asthma phenotype or specific biomarkers present. 

Treatment plans are personalized, and the choice of biologic therapy is determined by careful evaluation and consultation with a healthcare professional specializing in respiratory disorders.

Biologic infusion therapy is administered in healthcare settings under the supervision of trained medical professionals. Regular monitoring and follow-up appointments are essential to assess treatment effectiveness, adjust medication dosages if necessary, and ensure optimal management of severe asthma.

Contact Fuse Infusion for Treatment

If your doctor has recommended biologic infusion therapy treatment for severe asthma, we at Fuse Infusion offer you the best treatment services. We treat severe asthma through medications, which are specialized biologics, and help our patients in overcoming this chronic disease.

Each Fuse Infusion patient receives direct care and treatment from our licensed professionals throughout biological infusion therapy, providing thorough medical management.

From start to end, each patient receives individualized care. When required, on-call medical professionals are accessible.

At Fuse Infusion, we believe in offering premium-quality services to our patients. So, contact us to receive a biological infusion today!